135322-01-9

Basic information

• Product Name: 3-(BOC-AMINO)-4-HYDROXYBENZOIC ACID
• Synonyms: 3-(BOC-AMINO)-4-HYDROXYBENZOIC ACID;3-((tert-Butoxycarbonyl)aMino)-4-hydroxybenzoic acid
• CAS NO: 135322-01-9
• Molecular Formula: C₁₂H₁₅NO₅
• Molecular Weight: 253.25
• Mol File: 135322-01-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(BOC-AMINO)-4-HYDROXYBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(BOC-AMINO)-4-HYDROXYBENZOIC ACID(135322-01-9)
• EPA Substance Registry System: 3-(BOC-AMINO)-4-HYDROXYBENZOIC ACID(135322-01-9)

Safety Data

• Hazardous Substances Data: 135322-01-9(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1571-72-8 3-amino-4-hydroxybenzoic acid 

Relevant articles and documents

Continued Exploration of Trifunctional Alkyl 4-Chloro-2-diazo-3-oxobutanoates: Streamlined Entry into [1,2,3]Triazolo[5,1- c ][1,4]benzoxazines and [1,2,3]Triazolo[5,1- c ][1,4]benzoxazepines

Further exploration of the trifunctional character of previously introduced alkyl 4-chloro-2-diazo-3-oxobutanoates in reactions with N -protected substituted o -aminophenols followed by deprotection provided a convenient entry into [1,2,3]triazolo[5,1- c ][1,4]benzoxazines, which are of high medicinal importance, as documented in the literature. The same approach applied to N -protected substituted o -(aminomethyl)phenols afforded [1,2,3]triazolo[5,1- c ][1,4]benzoxazepines, which are practically unexplored compounds from a medicinal chemistry perspective. The syntheses start with S N 2-type alkylation of the phenol. Removal of the protecting group triggers imine formation followed by Wolff 1,2,3-triazole synthesis.

Non-natural macrocyclic inhibitors of histone deacetylases: Design, synthesis, and activity

Nonpeptidic chiral macrocycles were designed on the basis of an analogue of suberoylanilide hydroxamic acid (2) (SAHA, vorinostat) and evaluated against 11 histone deacetylase (HDAC) isoforms. The identification of critical amino acid residues highly cons

Novel benzoic and phenylacetic acid derivatives

The compound of the formula STR1 wherein R1, R2 and R3 have the significance given in the description, can be used as medicaments for the therapy and prophylaxis of disorders such as thromboses, stroke, cardiac infarct, inflammations and arteriosclerosis as well as for the treatment of tumours.