REACTION OF CHLORO DERIVATIVES OF 10-BENZYL- AND 10-(4'-FLUOROBENZYL)PHENOTHIAZINES WITH NITRILES AND AMINES UNDER ARYNE-FORMING CONDITIONS
2-Chloro-10-benzylphenothiazine (1) and 2-chloro-10-(4'-fluorobenzyl)phenothiazine (2) react with aliphatic nitriles (3 and 4) and LDA to yield typical 2-substituted aryne products (9a,b and 9g,h, respectively).However, treatment of 1 with aromatic nitril
Self, Jennifer L.,Khanapure, Subhash P.,Biehl, Edward R.
p. 311 - 318
(2007/10/02)
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