Sterically-Controlled Self-Immolation in Phosphoramidate Linkers Triggered by Light
Phosphoramidate prodrugs stand out for their applications as drug delivery systems. However, information on their activation remains limited to prodrug half-live and metabolite structure, which hinders their development. Considering the lack of data on ph
Wavelength-orthogonal photolysis of neurotransmitters in vitro
Irradiation of a mixture of 4-methoxyphenacyl-caged (S)-glutamate and 4,5-dimethoxy-2-nitrobenzyl-caged γ-amino butyric acid (GABA) on neurons, at ~260 nm, evokes selective photorelease of (S)-glutamate (Glu) whereas photolysis at 405 nm causes selective photorelease of GABA.
Stanton-Humphreys, Megan N.,Taylor, Ruth D. T.,McDougall, Craig,Hart, Mike L.,Brown, C. Tom A.,Emptage, Nigel J.,Conway, Stuart J.
supporting information; scheme or table
p. 657 - 659
(2012/02/02)
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