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1354359-53-7

JW 480 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1354359-53-7 Structure

  • Basic information

    1. Product Name: JW 480
    2. Synonyms: 2-Isopropylphenyl (2-(naphthalen-2-yl)ethyl)carbamate;Cancer Hydrolase KIAA1363 Inhibitor, JW480;JW 480;PCNJGBMWAZRVEA-UHFFFAOYSA-N
    3. CAS NO:1354359-53-7
    4. Molecular Formula: C22H23NO2
    5. Molecular Weight: 333.42352
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1354359-53-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: white to beige/
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: DMSO: soluble20mg/mL, clear
    9. CAS DataBase Reference: JW 480(CAS DataBase Reference)
    10. NIST Chemistry Reference: JW 480(1354359-53-7)
    11. EPA Substance Registry System: JW 480(1354359-53-7)

  • Safety Data

    1. Hazard Codes: T,N
    2. Statements: 25-50/53
    3. Safety Statements: 45-60-61
    4. RIDADR: UN 3077 9 / PGIII
    5. WGK Germany: 3
    6. RTECS:
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 1354359-53-7(Hazardous Substances Data)

1354359-53-7 Usage

Uses

JW 480 is a selective and potent inhibitor of KIAA1363, a serine hydrolase enzyme.

Check Digit Verification of cas no

The CAS Registry Mumber 1354359-53-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,4,3,5 and 9 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1354359-53:
(9*1)+(8*3)+(7*5)+(6*4)+(5*3)+(4*5)+(3*9)+(2*5)+(1*3)=167
167 % 10 = 7
So 1354359-53-7 is a valid CAS Registry Number.

1354359-53-7 Well-known Company Product Price

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  • (Code)Product description
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  • Detail

  • Sigma

  • (SML0792)  JW480  ≥98% (HPLC)

  • 1354359-53-7

  • SML0792-5MG

  • 995.67CNY

  • Detail

  • Sigma

  • (SML0792)  JW480  ≥98% (HPLC)

  • 1354359-53-7

  • SML0792-25MG

  • 4,014.27CNY

  • Detail

1354359-53-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Isopropylphenyl (2-(naphthalen-2-yl)ethyl)carbamate

1.2 Other means of identification

Product number -
Other names JW 480

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1354359-53-7 SDS

1354359-53-7Downstream Products

1354359-53-7Relevant articles and documents

ANTI-CANCER SERINE HYDROLASE INHIBITORY CARBAMATES

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Page/Page column 62, (2012/05/19)

Serine hydrolases are implicated in malconditions such as cancer, central nervous system disorders, cardiovascular disorders, obesity, and metabolic disorders. Many serine hydrolases expressed in proteomic libraries are of unknown function in vivo. Compounds identified through library versus library screening can be used for treatment of malconditions associated with the specific serine hydrolase KIAA1363 (also known as AADACL1). A library of inhibitors of KIAA1363 was prepared and candidate compounds were identified as a potent inhibitors having submicromolar IC50 values. An exemplary compound of the invention was shown to be an effective inhibitor of prostate cancer pathogenesis. Other inhibitory compounds of the invention comprising fluorophore groups are shown to be effective in spatial and temporal localization of the serine hydrolase in cells and tissues.

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