- Reaction of 4-amino-5-mercapto-1,2,4-triazoles with chalcone dibromides and α-bromochalcones
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Four α-bromochalcones (2) have been condensed with some 3-substituted-4-amino-5-mercapto-1,2,4-triazoles (3) in the presence of ethanolic KOH to yield hitherto unreported 6,8-diaryl-1,2,4-triazolothiadiazepines (4), whose structure has been established on the basis of analytical and spectral data.The chalcone dibromide (1) when treated with 4-amino-5-mercapto-1,2,4-triazoles (3) in the presence of triethylamine undergoes debromination to give the corresponding chalcones.
- Holla, B Shivarama,K, Shridhara,Kalluraya, Balakrishna
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p. 672 - 675
(2007/10/02)
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