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2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile is a chemical compound that is commonly used in organic synthesis. It is a nicotinonitrile derivative with a boronic ester functional group, making it a valuable reagent in palladium-catalyzed cross-coupling reactions. Known for its versatility in forming C-N, C-O, and C-C bonds, this compound is useful in the pharmaceutical and agrochemical industries for the synthesis of various biologically active compounds. Its unique structure and reactivity make it an important building block in organic chemistry for the preparation of complex molecules.

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  • 2-(morpholin-4-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carbonitrile

    Cas No: 1356068-62-6

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  • 1356068-62-6 Structure
  • Basic information

    1. Product Name: 2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile
    2. Synonyms: 2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile;3-Cyano-2-morpholinopyridine-5-boronic acid, pinacol ester
    3. CAS NO:1356068-62-6
    4. Molecular Formula: C16H22BN3O3
    5. Molecular Weight: 315.17518
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1356068-62-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Refrigerated.
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile(1356068-62-6)
    11. EPA Substance Registry System: 2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile(1356068-62-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1356068-62-6(Hazardous Substances Data)

1356068-62-6 Usage

Uses

Used in Pharmaceutical Industry:
2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile is used as a key intermediate for the synthesis of pharmaceutical compounds. Its ability to form various types of bonds makes it suitable for creating complex molecular structures that can exhibit therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile is used as a precursor for the development of agrochemicals. Its reactivity in forming different types of bonds allows for the creation of molecules with potential applications in crop protection and pest control.
Used in Organic Synthesis:
2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile is used as a reagent in palladium-catalyzed cross-coupling reactions. Its boronic ester functional group enables the formation of C-N, C-O, and C-C bonds, making it a versatile building block for the synthesis of complex organic molecules.

Check Digit Verification of cas no

The CAS Registry Mumber 1356068-62-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,6,0,6 and 8 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1356068-62:
(9*1)+(8*3)+(7*5)+(6*6)+(5*0)+(4*6)+(3*8)+(2*6)+(1*2)=166
166 % 10 = 6
So 1356068-62-6 is a valid CAS Registry Number.

1356068-62-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-morpholin-4-yl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carbonitrile

1.2 Other means of identification

Product number -
Other names 2-Morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1356068-62-6 SDS

1356068-62-6Downstream Products

1356068-62-6Relevant articles and documents

WDR5 INHIBITORS AND MODULATORS

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, (2018/04/20)

Described are compounds that disrupt the WDR5-MLL1 protein-protein interaction, pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating disorders and conditions in a subject.

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