- Oxazole quinoline derivatives, preparation method and in preparing plant pathogenic fungi in the application of the antimicrobial agent
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The invention discloses an oxazoline derivative and a preparation method and application of the oxazoline derivative and the preparation method in preparing an antibacterial agent of plant pathogenic fungi. A structural formula of the oxazoline derivative is shown in a formula I, wherein the substituent group R is H or 6-Me or 5-CN or 5-NO2, the substituent group R is H or p-Me or p-Cl, and the substituent group R is Me or Et. According to the oxazoline derivative and the preparation method and the application of the oxazoline derivative and the preparation method in preparing the antibacterial agent of the plant pathogenic fungi, a new 2-alkyl-2-(N-benzenesulfonylindol-3-yl)-3-N-acetyl-5-phenyl-1,3,4-oxazoline derivative is provided, and the preparation method of compounds is provided. The obtained 2-alkyl-2-(N-benzenesulfonylindol-3-yl)-3-N-acetyl-5-phenyl-1,3,4-oxazoline derivative has better antibacterial activity on the plant pathogenic fungi, the antibacterial activity of most of the compounds is higher than that of the commercially available antibacterial hymexazol, and the oxazoline derivative can be used for preparing the novel efficient antibacterial agent of the plant pathogenic fungi.
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