135641-62-2

Basic information

• Product Name: 1H-Pyrazole-1,3-dicarboxylic acid, dimethyl ester (9CI)
• Synonyms: 1H-Pyrazole-1,3-dicarboxylic acid, dimethyl ester (9CI)
• CAS NO: 135641-62-2
• Molecular Formula: C7H8N2O4
• Molecular Weight: 184.15
• Mol File: 135641-62-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Pyrazole-1,3-dicarboxylic acid, dimethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-1,3-dicarboxylic acid, dimethyl ester (9CI)(135641-62-2)
• EPA Substance Registry System: 1H-Pyrazole-1,3-dicarboxylic acid, dimethyl ester (9CI)(135641-62-2)

Safety Data

• Hazardous Substances Data: 135641-62-2(Hazardous Substances Data)

Upstream product

• 135641-60-0 3,3-bis(methoxycarbonyl)-3H-pyrazole 
• 38238-77-6 dimethyl 2-chloroethylene-1,1-dicarboxylate 
• 135641-58-6 4-chloro-3,3-bis(methoxycarbonyl)-4,5-dihydro-3H-pyrazole 

Relevant articles and documents

Effect of Electron-withdrawing Groups on the Thermal Ring Opening of 3H-Pyrazoles to Diazoalkenes

3-Cyano-3H-pyrazoles, bearing a cyano, a p-chlorophenyl, or a p-chlorobenzyl group at C-3, generated from elimination reaction of the corresponding dihydropyrazoles with a leaving group such as a chlorine or p-chlorobenzoyloxy group, gave diazolkene derivatives, resulting from the ring-opening of the 3H-pyrazoles.However, 3-methoxycarbonyl-3H-pyrazoles bearing a methoxycarbonyl, a p-chlorophenyl, or p-chlorobenzyl group at C-3, prepared in a similar manner, gave mainly 1-methoxycarbonyl-1H-pyrazole derivatives, resulting from migration of the 3-methoxycarbonyl group to the adjacent nitrogen within the generated 3H-pyrazoles.Treatment of 3H-pyrazoles (8a and 29b) and 5-substituted 1-methoxycarbonyl-1H-pyrazoles (10a and 31b) with triethylamine gave 3-substituted 1-methoxycarbonyl-1H-pyrazoles, resulting from migration of the methoxycarbonyl group to the remote nitrogen.