1356542-52-3Relevant articles and documents
Synthesis of annulated pyridines by intramolecular inverse-electron-demand hetero-diels-alder reaction under superheated continuous flow conditions
Martin, Rainer E.,Morawitz, Falk,Kuratli, Christoph,Alker, Andre M.,Alanine, Alexander I.
, p. 47 - 52 (2012/01/14)
Pyrimidine alkynes can be transformed into the corresponding annulated pyridines efficiently in flow. The superheating of organic solvents far beyond their boiling point enables toxic and difficult to workup solvents such as nitrobenzene or chlorobenzene,