Synthesis of δ-Bromo γ,δ-unsaturated carbonyl compounds via palladium-catalyzed bromoalkylation of alkynoates
Palladium-catalyzed regio- and stereoselective intermolecular tandem reaction of electron-deficient alkynes, CuBr2, and allylic alcohol to synthesize δ-bromo-γ,δ-unsaturated carbonyls was developed. A mechanism involving bromopalladation of alk