1357946-70-3 Usage
Uses
Used in Pharmaceutical Industry:
4-b]pyridine is used as a potential therapeutic agent for the treatment of autoimmune diseases and cancer due to its ability to inhibit the enzyme dihydroorotate dehydrogenase. This inhibition can disrupt the synthesis of pyrimidine nucleotides, which are essential for the rapid proliferation of immune cells and cancer cells, thereby potentially controlling the progression of these diseases.
Used in Agricultural Industry:
4-b]pyridine is used as a potential herbicide for weed control. Its herbicidal properties can help in managing unwanted plant growth in agricultural fields, thereby improving crop yield and quality.
Check Digit Verification of cas no
The CAS Registry Mumber 1357946-70-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,7,9,4 and 6 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1357946-70:
(9*1)+(8*3)+(7*5)+(6*7)+(5*9)+(4*4)+(3*6)+(2*7)+(1*0)=203
203 % 10 = 3
So 1357946-70-3 is a valid CAS Registry Number.
1357946-70-3Relevant articles and documents
INHIBITORS OF BRUTON'S TYROSINE KINASE
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Paragraph 00851-00852, (2016/01/25)
Disclosed herein are compounds that inhibit Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. In addition, reversible inhibitors of Btk are also described. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
Compounds as syk kinase inhibitors
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Paragraph 0772; 0773; 0774, (2013/03/26)
The present invention relates to a compound of formula (I), to the process for preparing such compounds and to their use in the treatment of a pathological condition or disease susceptible to amelioration by inhibition of Syk kinase.
