135821-74-8Relevant articles and documents
Reverse-electron-demand diels-alder dienophile π-face selectivity via conformation dependent transmission of π-σ-π electronic interactions
Garcia, J. Gabriel,McLaughlin, Mark L.
, p. 3293 - 3296 (2007/10/02)
Reverse-electron-demand Diels-Alder reactions of a series of remotely substituted cyclooctenes with hexachlorocyclopentadiene and 5,5-dimethoxy-1,2,3,4-tetrachlorocyclopenta-2,4-diene indicate that dienophile π-face selectivity results from conformation dependent transmission of π-G-π electronic interactions.
Tandem reverse-electron-demand Diels-Alder reactions of 1,5-cyclooctadiene
Garcia,Fronczek,McLaughlin
, p. 3289 - 3292 (2007/10/02)
Hexachlorocyclopentadiene and 5,5-dimethoxy-1,2,3,4-tetrachlorocyclopenta-2,4-diene react with 1,5-cyclooctadiene to produce a 1:4 syn to anti mixture of diadducts in good yield. The stereochemistry of the diastereomers is examined using X-ray and molecular mechanics calculations are used to explore some of the potential causes for the observed diastereoselectivity.