Copper-catalyzed aerobic [3+2]-annulation of N -alkenyl amidines
A method for the synthesis of bi- and tricyclic amidines has been developed through copper-catalyzed aerobic [3+2]-annulation reaction of N-alkenyl amidines. These cyclic amidines could be converted into mono-benzyl-protected vicinal diamines by the reduction with aluminum hydride.
Wang, Yi-Feng,Zhu, Xu,Chiba, Shunsuke
p. 3679 - 3682
(2012/04/11)
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