136091-68-4

Basic information

• Product Name: 4-BROMO-1-BUTANOL-1,1,2,2,3,3,4,4-D8
• Synonyms: 4-BROMO-1-BUTANOL-1,1,2,2,3,3,4,4-D8;4-BroMo-1-butanol--d8
• CAS NO: 136091-68-4
• Molecular Formula: C4HBrD8O
• Molecular Weight: 161.07
• Mol File: 136091-68-4.mol

Chemical Properties

• Boiling Point: 190.932 °C at 760 mmHg
• Flash Point: 92.102 °C
• Appearance: /
• Density: 1.53 g/cm³
• CAS DataBase Reference: 4-BROMO-1-BUTANOL-1,1,2,2,3,3,4,4-D8(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-1-BUTANOL-1,1,2,2,3,3,4,4-D8(136091-68-4)
• EPA Substance Registry System: 4-BROMO-1-BUTANOL-1,1,2,2,3,3,4,4-D8(136091-68-4)

Safety Data

• Hazardous Substances Data: 136091-68-4(Hazardous Substances Data)

Usage

Uses

Used in Research and Development:
4-BROMO-1-BUTANOL-1,1,2,2,3,3,4,4-D8 is used as a research compound for investigating the properties and behavior of molecules in various chemical and biological processes. The presence of deuterium atoms in its structure allows for a better understanding of the effects of isotopic substitution on molecular interactions and reaction kinetics.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-BROMO-1-BUTANOL-1,1,2,2,3,3,4,4-D8 is used as a labeled compound for studying drug metabolism and pharmacokinetics. The deuterated version of the molecule can help researchers identify and track the metabolic pathways of drugs, leading to a better understanding of their efficacy and potential side effects.
Used in Chemical Synthesis:
4-BROMO-1-BUTANOL-1,1,2,2,3,3,4,4-D8 is also used as a starting material or intermediate in the synthesis of various organic compounds. The deuterated nature of the compound can be advantageous in specific synthetic routes, where the presence of deuterium can influence the reaction outcomes or provide insights into reaction mechanisms.
Used in Analytical Chemistry:
In analytical chemistry, 4-BROMO-1-BUTANOL-1,1,2,2,3,3,4,4-D8 can be employed as an internal standard or a reference compound for quantitative analysis. The deuterated molecule can be used to improve the accuracy and precision of measurements, particularly in techniques such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy.
Used in Environmental Studies:
4-BROMO-1-BUTANOL-1,1,2,2,3,3,4,4-D8 can be utilized in environmental research to study the fate and transport of pollutants in the environment. The deuterated compound can serve as a tracer to track the movement and transformation of contaminants in various environmental matrices, such as water, soil, and air.

Upstream product

• 1693-74-9 tetrahydrofuran-d8 
• 136118-84-8 1,1,2,2,3,3,4,4-d8-4-bromobutyl acetate 

Relevant articles and documents

Unusual Adsorption at the Air-Water Interface of a Zwitterionic Carboxybetaine with a Large Charge Separation

The structures of layers of three different dodecylcarboxybetaine surfactants adsorbed at the air-water interface have been determined by neutron reflection. The zwitterionic compounds differed in the length of the spacer separating the quaternary ammonium and carboxylate groups, which was (CH2)1, (CH2)4, or (CH2)8. The limiting area per molecule was found to be 45, 52, or 84 ?2, respectively, and compared reasonably with results from surface tension showing that the Gibbs prefactor is 1 in each case. Isotopic labeling was used to distinguish between the position of the alkyl and spacer groups in the layer. The spacer was found to be well-immersed in water for the (CH2)1 and (CH2)4 spacers but significantly above water for the (CH2)8 spacer. The distribution of the (CH2)8 spacer along the surface normal was found to be similar to that of the dodecyl group; i.e., it projects out of the water, contrary to an earlier hypothesis that it forms a loop. Comparison of the overlap of water with dodecyl and spacer groups also indicates that the (CH2)8 spacer is well out of the water. This in turn suggests that the anionic carboxylic acid group, which is dissociated in solution, is not ionized in the adsorbed layer. A further observation is that the dodecylcarboxybetaine with the (CH2)8 spacer reaches surface saturation at one-tenth of the critical micelle concentration. This is highly unusual and is attributed to the long spacer destabilizing the micelle relative to the surface layer.

SUBSTITUTED DIPHENYLPYRAZINE DERIVATIVES

This invention relates to novel substituted diphenylpyrazines and pharmaceutically acceptable salts thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering a PGI2 receptor agonist.