A convenient cyclopropanation process of oxindoles via bromoethylsulfonium salt
A practical convenient conversion of oxindoles into the corresponding spirocyclopropyl oxindoles is achieved efficiently using bromoethylsulfonium salt, which is easily prepared on a large scale and is stable crystalline. This reaction of bromoethylsulfonium salt with different substituted unprotected oxindoles proceeded under mild condition and provided moderate yields.
Domino Corey-Chaykovsky Reaction for One-Pot Access to Spirocyclopropyl Oxindoles
The development of the sequential Corey-Chaykovsky reactions of isatins, spiroepoxy-, or spiroaziridine oxindoles with sulfur ylide has led to the discovery of a unique reaction mode that allows easy and direct one-pot access to a range of spirocyclopropyl oxindoles.
Hajra, Saumen,Roy, Sayan,Saleh, S.K. Abu
supporting information
p. 4540 - 4544
(2018/08/07)
More Articles about upstream products of 1360946-84-4