A facile synthesis of 3-(substituted benzyl)piperidines
A convenient new method has been developed for preparation a series of 3-(substituted benzyl)piperidines by addition of substituted phenylmagnesium bromide to pyridine-3-carboxaldehyde followed by one pot deoxygenation and heteroaromatic ring saturation in the presence of palladium catalyst.
ágai, Béla,Nádor, Adrienn,Proszenyák, ágnes,Tárkányi, Gábor,Faigl, Ferenc
p. 7897 - 7900
(2007/10/03)
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