Binding of Substituted and Conformationally Restricted Derivatives of N-(3-Phenyl-n-propyl)-1-phenyl-2-aminopropane at ?-Receptors
Certain benzomorphans, such as N-allylnormetazocine, are classical "?-opiates" that bind both at ? and phencyclidine (PCP) binding sites with modest affinity.Recently, we identified N-substituted 2-phenylaminoethane as being the primary ?-pharmacophore of
Glennon, Richard A.,Ismaiel, Abd M.,Smith, J. Doyle,Yousif, Mamoun,El-Ashmawy, Mahmoud,et al.
p. 1855 - 1859
(2007/10/02)
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