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2,8-dichloro-7-nitro-1,5-naphthyridine is a chemical compound with a molecular formula C10H5Cl2N3O2. It is a nitro-substituted naphthyridine derivative known for its potent antimicrobial and antifungal properties, making it a valuable ingredient in the development of antibacterial and antifungal medications. Its unique chemical structure and reactivity make it a versatile building block in organic synthesis, allowing for the creation of diverse molecular structures with potential pharmacological applications.

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  • 1366050-48-7 Structure
  • Basic information

    1. Product Name: 2,8-dichloro-7-nitro-1,5-naphthyridine
    2. Synonyms: 2,8-dichloro-7-nitro-1,5-naphthyridine
    3. CAS NO:1366050-48-7
    4. Molecular Formula: C8H3Cl2N3O2
    5. Molecular Weight: 244.03432
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1366050-48-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 364.6±37.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.674±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: -2.80±0.10(Predicted)
    10. CAS DataBase Reference: 2,8-dichloro-7-nitro-1,5-naphthyridine(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2,8-dichloro-7-nitro-1,5-naphthyridine(1366050-48-7)
    12. EPA Substance Registry System: 2,8-dichloro-7-nitro-1,5-naphthyridine(1366050-48-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1366050-48-7(Hazardous Substances Data)

1366050-48-7 Usage

Uses

Used in Pharmaceutical Industry:
2,8-dichloro-7-nitro-1,5-naphthyridine is used as a synthetic intermediate for the production of pharmaceuticals. Its potent antimicrobial and antifungal properties make it a valuable component in the development of antibacterial and antifungal medications.
Used in Organic Synthesis:
2,8-dichloro-7-nitro-1,5-naphthyridine is used as a versatile building block in organic synthesis. Its unique chemical structure and reactivity allow for the creation of diverse molecular structures with potential pharmacological applications.
It is important to handle 2,8-dichloro-7-nitro-1,5-naphthyridine with caution, as it may pose certain risks to human health and the environment if not used properly.

Check Digit Verification of cas no

The CAS Registry Mumber 1366050-48-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,6,0,5 and 0 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1366050-48:
(9*1)+(8*3)+(7*6)+(6*6)+(5*0)+(4*5)+(3*0)+(2*4)+(1*8)=147
147 % 10 = 7
So 1366050-48-7 is a valid CAS Registry Number.

1366050-48-7Downstream Products

1366050-48-7Relevant articles and documents

KETONE DERIVATIVES OF IMIDAZOLES, PHARMACEUTICAL COMBINATIONS AND USES THEREOF

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Paragraph 0300; 0301, (2016/10/06)

This application relates to ketone compounds of imidazoles, pharmaceutically acceptable salts, solvents, polymorphs or prodrugs thereof, and further relates to pharmaceutical combinations comprising the foregoing substances and uses for preventing and treating protein kinase related diseases such as cancer, metabolic diseases, and cardiovascular diseases.

Imidazole derivatives, its pharmaceutical composition and use thereof

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Paragraph 0695-0697, (2017/02/24)

Imidazolone compounds, pharmaceutically acceptable salts, solvates, polymorphs or prodrugs thereof are disclosed. Pharmaceutical compositions comprising above substances and uses for preventing and treating protein kinases related diseases, such as cancers, metabolic diseases, cardiovascular diseases and the like, are also disclosed.

FUSED HETEROARYLS AND THEIR USES

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Paragraph 0174; 0175, (2013/07/31)

Provided are certain fused heteroaryls, compositions thereof and methods of use therefor.

FUSED HETEROARYLS AND THEIR USES

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Page/Page column 37, (2012/04/04)

Provided are certain fused heteroaryls, compositions thereof and methods of use therefor.

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