1367369-80-9

Basic information

• Product Name: (1'S,3'S,4'S)-Entecavir IsoMer
• Synonyms: 2-AMino-1,9-dihydro-9-[(1S,3R,4R)-4-hydroxy-3-(hydroxyMethyl)-2-Methylenecyclopentyl]-6H-purin-6-one;4'-epi-Entecavir;Entecavir IsoMer 2;4-Epimer Entecavir (Entecavir EP Impurity D);2-amino-9-((1S,3R,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1,9-dihydro-6H-purin-6-one hydrate;(1'S,3'S,4'S)-Entecavir;Entecavir (1S,3R,4R) Diastereomer;(1'S,3'S,4'S)-Entecavir IsoMer
• CAS NO: 1367369-80-9
• Molecular Formula: C12H15N5O3
• Molecular Weight: 277.2792
• Product Categories: Anti-virals, Chiral Reagents, Heterocycles, Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals;Anti-virals;Bases & Related Reagents;Chiral Reagents;Heterocycles;Impurities;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals
• Mol File: 1367369-80-9.mol

Chemical Properties

• Boiling Point: 661.4±65.0 °C(Predicted)
• Appearance: /
• Density: 1.81±0.1 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer
• Solubility: DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
• PKA: 14.22±0.60(Predicted)
• CAS DataBase Reference: (1'S,3'S,4'S)-Entecavir IsoMer(CAS DataBase Reference)
• NIST Chemistry Reference: (1'S,3'S,4'S)-Entecavir IsoMer(1367369-80-9)
• EPA Substance Registry System: (1'S,3'S,4'S)-Entecavir IsoMer(1367369-80-9)

Safety Data

• Hazardous Substances Data: 1367369-80-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Amino-1,9-dihydro-9-((1S,3R,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-6H-purin-6-one is used as an impurity reference for the antiviral drug Entecavir. Its presence in the drug formulation is crucial for quality control and ensuring the safety and efficacy of the medication.
Used in Research and Development:
2-Amino-1,9-dihydro-9-((1S,3R,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-6H-purin-6-one serves as a valuable research tool for scientists and researchers working on the development of new antiviral drugs. It can be used to study the structure-activity relationship of Entecavir and other related compounds, leading to the discovery of more effective and safer treatments for viral infections.
Used in Quality Control and Analysis:
2-Amino-1,9-dihydro-9-((1S,3R,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-6H-purin-6-one is used in the quality control and analysis of pharmaceutical products containing Entecavir. It helps in the identification, quantification, and monitoring of impurities in the drug, ensuring that the final product meets the required standards and specifications.