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CAS

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136835-01-3

N-(4-[(E)-3-(4-CHLOROPHENYL)-3-OXO-1-PROPENYL]PHENYL)ACETAMIDE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 136835-01-3 Structure

  • Basic information

    1. Product Name: N-(4-[(E)-3-(4-CHLOROPHENYL)-3-OXO-1-PROPENYL]PHENYL)ACETAMIDE
    2. Synonyms: N-(4-[(E)-3-(4-CHLOROPHENYL)-3-OXO-1-PROPENYL]PHENYL)ACETAMIDE;4'-(2-(4-CHLOROBENZOYL)-VINYL)-ACETANILIDE
    3. CAS NO:136835-01-3
    4. Molecular Formula: C17H14ClNO2
    5. Molecular Weight: 299.75
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 136835-01-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-(4-[(E)-3-(4-CHLOROPHENYL)-3-OXO-1-PROPENYL]PHENYL)ACETAMIDE(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-(4-[(E)-3-(4-CHLOROPHENYL)-3-OXO-1-PROPENYL]PHENYL)ACETAMIDE(136835-01-3)
    11. EPA Substance Registry System: N-(4-[(E)-3-(4-CHLOROPHENYL)-3-OXO-1-PROPENYL]PHENYL)ACETAMIDE(136835-01-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 136835-01-3(Hazardous Substances Data)

136835-01-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 136835-01-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,8,3 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 136835-01:
(8*1)+(7*3)+(6*6)+(5*8)+(4*3)+(3*5)+(2*0)+(1*1)=133
133 % 10 = 3
So 136835-01-3 is a valid CAS Registry Number.

136835-01-3Downstream Products

136835-01-3Relevant articles and documents

Antifungal activity of chalcones: A mechanistic study using various yeast strains

Lahtchev,Batovska,Parushev,Ubiyvovk,Sibirny

, p. 2220 - 2228 (2008/12/23)

We reported the synthesis, antifungal evaluation and study on substituent effects of 21 chalcones. A lot of genetically defined strains belonging to different yeast genera and species, namely Saccharomyces cerevisiae, Hansenula polymorpha and Kluyveromyces lactis, were used as test organisms. Concerning the mode of the antifungal action of chalcones it was shown that DNA was probably not the main target for the chalcones. It was revealed that the yeast's intracellular glutathione and cysteine molecules play significant role as defence barrier against the chalcone action. It was also shown that chalcones may react with some proteins involved in cell separation.

Study on the substituents' effects of a series of synthetic chalcones against the yeast Candida albicans

Batovska,Parushev,Slavova,Bankova,Tsvetkova,Ninova,Najdenski

, p. 87 - 92 (2007/10/03)

A large series of chalcones were synthesized and studied for activity against Candida albicans. The SAR analysis showed that the antifungal activity was highly dependent on the substitution pattern of the aryl rings and correlated to a large extent with the ability of compounds to interact with sulfhydryl groups. The most active were the hydroxylated chalcones as their activity related to the location of the phenolic group in the aryl ring B as follows: o-OH > p-OH ～ 3,4-di-OH > m-OH. These and other correlations obtained strongly contribute to the knowledge for design of anticandidal chalcones.

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