136864-16-9 Usage
Uses
1. Used in Metabolic Processes:
D-[5-2H]GLUCOSE is used as a substrate for various metabolic processes, including the enzymic synthesis of cyclohexyl-α and β-D-glucosides. This application is crucial for studying and understanding the biochemical pathways and reactions involving glucose in living organisms.
2. Used in Diagnostics for Type 2 Diabetes Mellitus:
D-[5-2H]GLUCOSE is used as a diagnostic tool for the detection of type 2 diabetes mellitus. By analyzing blood-glucose levels, healthcare professionals can identify and monitor the progression of the disease, allowing for appropriate treatment and management strategies.
3. Used in Diagnostics for Potential Huntington's Disease:
D-[5-2H]GLUCOSE can also be used as a diagnostic tool in the detection of potentially Huntington's disease through the analysis of blood-glucose in type 1 diabetes mellitus. This application aids in the early identification and treatment of the neurodegenerative disorder.
4. Used in Photosynthesis Research:
As D-[5-2H]GLUCOSE plays a vital role in photosynthesis, it is used in research to study the process of energy conversion and the role of glucose in plant metabolism. This application is essential for understanding the fundamental mechanisms of plant growth and development.
5. Used in Cellular Respiration Studies:
D-[5-2H]GLUCOSE is used in cellular respiration studies to investigate the energy production processes in living organisms. This application helps researchers understand how glucose is utilized to generate energy for various cellular functions.
Check Digit Verification of cas no
The CAS Registry Mumber 136864-16-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,8,6 and 4 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 136864-16:
(8*1)+(7*3)+(6*6)+(5*8)+(4*6)+(3*4)+(2*1)+(1*6)=149
149 % 10 = 9
So 136864-16-9 is a valid CAS Registry Number.
136864-16-9Relevant articles and documents
Glucose is a precursor of 1-deoxynojirimycin and 1-deoxymannonojirimycin in Streptomyces subrutilus
Hardick, David J.,Hutchinson, David W.,Trew, Sally J.,Wellington, Elizabeth M. H.
, p. 6285 - 6296 (2007/10/02)
Streptomyces subrutilus ATCC 27467, when grown on a glucose-containing soyabean medium, produces both 1-deoxymannonojirimycin (DMJ) and 1-deoxynojirimycin (DNJ) in its culture medium. When 1- or 2-[2H]-D-glucose is used, the deuterium label appears at C6 in both alkaloids and the labelling pattern suggests that the first step in the biosynthesis of both DNJ and DMJ is a glucose to fructose isomerisation. Studies with 5-2H]- and 6,6-2H2-D-glucose indicate that oxidation of the 6-position of the glucose/fructose occurs during the biosynthesis and that mannonojirimycin is the first aminosugar to be formed. Mannonojirimycin can then undergo dehydration and reduction to DMJ. Alternatively, epimerisation of mannonojirimycin can occur at C2 to give nojirimycin which is then dehydrated and reduced to DNJ.
