Dipeptide Side-Chain Chain Hydrophobic Interactions as Conformational Core for Chymotrypsin Inhibition
A series of dipeptides with the sequence H-D-Leu-L-Phe-R denotes 4-phenylpiperidide, 4-phenylpiperazide, and their derivatives, have been synthesized to examine their ability to inhibit chymotrypsin.Dipeptide phenylpiperidide and phenylpiperazide inhibite