Synthesis and evaluation of some water-soluble prodrugs and derivatives of taxol with antitumor activity
The synthesis and evaluation of some 2'- and 7-amino acid derivatives of taxol (1) are reported. Reaction of taxol with N-protected amino acids gave 2'-N-protected amino acid esters of taxol. However, deprotection of the amino group and subsequent isolati
Mathew,Mejillano,Nath,Himes,Stella
p. 145 - 151
(2007/10/02)
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