137267-49-3Relevant articles and documents
The Oxidation of 2-Oxazolines to 1,3-Oxazoles
Meyers, A. I.,Tavares, Francis
, p. 2481 - 2484 (1994)
Oxazolines are readily oxidized to 1,3-oxazoles using NBS/peroxide or light or, more efficiently, by the Kharasch-Sosnovsky Reaction.
CpRu-catalyzed O-H insertion and condensation reactions of α-diazocarbonyl compounds
Austeri, Martina,Rix, Diane,Zeghida, Walid,Lacour, Jerome
supporting information; experimental part, p. 1394 - 1397 (2011/05/03)
[CpRu(CH3CN)3][PF6] and diimine ligands catalyze together the decomposition of α-diazocarbonyl compounds leading to O-H insertion and condensation reactions. In comparison with Rh(II) and Cu(I) complexes, the CpRu catalysts produce rapid and often more selective reactions. Promising enantioselectivities are obtained in dioxole syntheses.
Regioselectivity in the Lithiation of Methyl-substituted Thiazole- and Oxazole-Carboxylic Acids and Carboxamides: General Methods for the Elaboration of Trisubstituted Thiazoles and Oxazoles
Cornwall, Philip,Dell, Colin P.,Knight, David W.
, p. 2417 - 2428 (2007/10/02)
A number of anionic intermediates have been developed which are suitable for the elaboration of trisubstituted thiazoles and oxazoles.Thus, deprotonation of 2,4-dimethylthiazole-5-carboxylic acid 9 using either BuLi or LDA occurs regiospecifically at the