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1374602-25-1

C30H38ClN5O2 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1374602-25-1 Structure

  • Basic information

    1. Product Name: C30H38ClN5O2
    2. Synonyms:
    3. CAS NO:1374602-25-1
    4. Molecular Formula:
    5. Molecular Weight: 536.117
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1374602-25-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C30H38ClN5O2(CAS DataBase Reference)
    10. NIST Chemistry Reference: C30H38ClN5O2(1374602-25-1)
    11. EPA Substance Registry System: C30H38ClN5O2(1374602-25-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1374602-25-1(Hazardous Substances Data)

1374602-25-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1374602-25-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,4,6,0 and 2 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1374602-25:
(9*1)+(8*3)+(7*7)+(6*4)+(5*6)+(4*0)+(3*2)+(2*2)+(1*5)=151
151 % 10 = 1
So 1374602-25-1 is a valid CAS Registry Number.

1374602-25-1Downstream Products

1374602-25-1Relevant articles and documents

Design, synthesis, and biological activity of novel 1,4-disubstituted piperidine/piperazine derivatives as CCR5 antagonist-based HIV-1 entry inhibitors

Dong, Ming-Xin,Lu, Lu,Li, Haitao,Wang, Xiaohua,Lu, Hong,Jiang, Shibo,Dai, Qiu-Yun

scheme or table, p. 3284 - 3286 (2012/06/18)

A series of novel 1,4-disubstituted piperidine/piperazine derivatives were designed, synthesized and evaluated for their in vitro activities against HIV-1 Bal (R5) infection in CEMX174 5.25M7 cells. A majority of these compounds showed potent anti-HIV-1 activities with IC50 at nanomolar levels. N-(4-Fluoro-benzyl)piperazine analog B07 hydrochloride exhibited potency against HIV-1 activity similar to that of TAK-220 hydrochloride, but it had much better water solubility (25 mg/ml in phosphate sodium buffer at 25 °C) and oral bioavailability (56%) than TAK-220 hydrochloride (a solubility of 2 mg/ml and oral bioavailability of 1.4%). These results suggest that B07 hydrochloride may serve as a better lead for the development of new anti-HIV-1 therapies or microbicides for treatment and prevent of HIV-1 infection.

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