Chelation Control in the Aldol Reaction of Tetronic Acid. Application to the Synthesis of Pentoses, Arabitol and Ribitol
The aldol reaction of lithium enolates of tetronates with (R)-2,3-O-cyclohexylideneglyceraldehyde afforded the chelation controlled products stereoselectively.The conversion of the aldol products into arabitol and ribitol was also described.