The present invention relates to novel substituted pyrimidobenzimidazole derivatives of the formula STR1 wherein the substituents are as described in the specification, and pharmaceutically acceptable salts thereof. The products have an inhibitory action
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(2008/06/13)
Pyrimido[1,6-a]benzimidazoles: A new class of DNA gyrase inhibitors
Substituted 4-quinolone- (1, A = CH) and 1,8-naphthyrid-4-one- (1, A = N) 3-carboxylic acids are currently the only classes of clinically useful antibacterial agents exerting their activity by inhibiting the subunit A of DNA gyrase. Pyrimido[1,6-a]benzimi