Rapid, stable, chemoselective labeling of thiols with Julia- Kocienski-like reagents: A serum-stable alternative to maleimide-based protein conjugation
Exquisite chemoselectivity for cysteine has been found for methylsulfonylphenyloxadiazole compounds under various buffer conditions. Furthermore, the resulting protein conjugates have superior stability to cysteine-maleimide conjugates in human plasma (HS
Toda, Narihiro,Asano, Shigehiro,Barbas, Carlos F.
supporting information
p. 12592 - 12596
(2013/12/04)
Methylsulfonyl benzothiazole (MSBT): A selective protein thiol blocking reagent
A new thiol blocking reagent, methylsulfonyl benzothiazole, was discovered. This reagent showed good selectivity and high reactivity for protein thiols.
Zhang, Dehui,Devarie-Baez, Nelmi O.,Li, Qian,Lancaster Jr., Jack R.,Xian, Ming
scheme or table
p. 3396 - 3399
(2012/08/08)
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