Studies on analgesic oligopeptides. VII. Solid phase synthesis and biological properties of Tyr-D-Arg-Phe-βAla-NH2 and its fluorinated aromatic amino acid derivatives
Tyr-D-Arg-Phe-βAla-NH2 (I) and its six fluorinated analogs were synthesized. Their opioid receptor binding properties were examined in vitro and their analgesic activity in vivo using the mouse writhing test. It was found that I was one of the
Sasaki,Ambo,Suzuki
p. 2316 - 2318
(2007/10/02)
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