- Palladium-Catalyzed Regio- and Stereoselective Coupling-Addition of Propiolates with Arylsulfonyl Hydrazides: A Pattern for Difunctionalization of Alkynes
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A new pattern for difunctionalization of alkynes via a palladium-catalyzed regio- and stereoselective coupling-addition of propiolates with arylsulfonyl hydrazides is disclosed. The approach enables the synthesis of various highly functionalized (E)-vinylsulfones in satisfactory yields. Arylsulfonyl hydrazides act as both aryl and sulfonyl sources via selective cleavage of Ar(C)-S and S-N bonds, which are simultaneously incorporated onto the terminal carbon atom of an alkyne molecule.
- Liu, Lixin,Sun, Kang,Su, Lebin,Dong, Jianyu,Cheng, Lei,Zhu, Xiaodong,Au, Chak-Tong,Zhou, Yongbo,Yin, Shuang-Feng
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supporting information
p. 4023 - 4027
(2018/07/15)
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- Polymerizable liquid crystal compound, an optical film and the liquid crystal composition containing the same
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The present invention relates to a polymerizable liquid crystal compound, a liquid crystal composition including the same, and an optical film including the same. The polymerizable liquid crystal compound according to the present invention has at least two functional groups making intermolecular interaction possible in its molecule, and thus it is possible to form a liquid crystal layer having high orientation stability by coating the composition including the same. According to this, the optical film prepared by using the composition can be suitably used in anti-reflection films and so on for liquid crystal displays or OLED displays.
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Paragraph 0103
(2017/01/05)
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- Gold-catalyzed formal [4π+2π]-cycloadditions of tert-butyl propiolates with aldehydes and ketones to form 4H-1,3-dioxine derivatives
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Gold-catalyzed formal hetero-[4π+2π] cycloadditions of tert-butyl propiolates with carbonyl compounds proceeded efficiently to yield 4H-1,3-dioxine derivatives over a wide scope of substrates. With acetone as a promoter, gold-catalyzed cycloadditions of these propiolate derivatives with enol ethers led to the formation of atypical [4+2]-cycloadducts with skeletal rearrangement.
- Karad, Somnath Narayan,Chung, Wei-Kang,Liu, Rai-Shung
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supporting information
p. 13004 - 13007
(2015/08/06)
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- Asymmetric synthesis of the cis- And trans-stereoisomers of 4-aminopyrrolidine-3-carboxylic acid and 4-aminotetrahydrofuran-3-carboxylic acid
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The diastereoselective conjugate addition of lithium (S)-N-benzyl-N- α-methylbenzylamide has been successfully applied to the first asymmetric syntheses of cis-(3S,4R)- and fraBs-(3R,4R)-4-arninotetrahydrofuran-3-carboxylic acids (26% and 25% overall yield respectively, >98% d.e. and >97% e.e. in each case). Furthermore, the most efficient asymmetric synthesis to date of cis-(3R,4R)- and trans-(3R,4S)-4-aminopyrrolidine carboxylic acids is delineated: for cis-(3R,4R), four steps, >98% d.e., 52% overall yield; for trans-(3R,4S), five steps, >98% d.e., 50% overall yield.
- Bunnage, Mark E.,Davies, Stephen G.,Roberts, Paul M.,Smith, Andrew D.,Withey, Jonathan M.
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p. 2763 - 2776
(2007/10/03)
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