Enantioselective copper-catalyzed construction of aryl pyrroloindolines via an arylation-cyclization cascade
An enantioselective arylation-cyclization cascade has been accomplished using a combination of diaryliodonium salts and asymmetric copper catalysis. These mild catalytic conditions provide a new strategy for the enantioselective construction of pyrroloindolines, an important alkaloid structural motif that is commonly found among biologically active natural products.
Zhu, Shaolin,MacMillan, David W. C.
p. 10815 - 10818
(2012/08/07)
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