138668-26-5

Basic information

• Product Name: (2R,3R)-2-nitropentan-3-ol
• CAS NO: 138668-26-5
• Molecular Formula: C₅H₁₁NO₃
• Molecular Weight: 133.1457
• Mol File: 138668-26-5.mol

Chemical Properties

• Boiling Point: 215.8°C at 760 mmHg
• Flash Point: 94.3°C
• Density: 1.09g/cm³
• Vapor Pressure: 0.0314mmHg at 25°C
• Refractive Index: 1.447
• CAS DataBase Reference: (2R,3R)-2-nitropentan-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-2-nitropentan-3-ol(138668-26-5)
• EPA Substance Registry System: (2R,3R)-2-nitropentan-3-ol(138668-26-5)

Safety Data

• Hazardous Substances Data: 138668-26-5(Hazardous Substances Data)

Upstream product

• 79-24-3 Nitroethane 
• 123-38-6 propionaldehyde 

Relevant articles and documents

Synthesis, crystal structure and catalytic properties in the diastereoselective nitroaldol (Henry) reaction of new zinc(II) and cadmium(II) compounds

The new complex [Zn(im)4](NO3)2 (1) was synthesized and crystallographically characterized. In the solid state, 1 is built up by [Zn(C3H4N2)]2+ cations and NO3?/

Nitroaldol reaction catalyzed by arylhydrazone di- and triorganotin(IV) complexes

Two known organotin(IV) complexes, [Sn(C6H5)3HL1] (1, H2L1 = 2-(2-(2,4-dioxopentan-3-ylidene)hydrazinyl)benzoic acid) and [Sn(C2H5)2(1κO,2κO-H3L

The Henry reaction catalyzed by NiII and CuII complexes bearing arylhydrazones of acetoacetanilide

The new nickel coordination polymer [Ni(HL1) (CH3OH)2]n (1) and co-crystal H3L1?DMF (2) were obtained by reaction of NiCl2·2H2O with 2-(2-(1,3-dioxo-1-(phenylamino)but

Mononuclear nickel(II) complexes with arylhydrazones of acetoacetanilide and their catalytic activity in nitroaldol reaction

The new mononuclear nickel(II) complexes [Ni(HL1)(H2O)2(CH3OH)] (1, NaH2L1 = sodium (Z)-2-(2-(1,3-dioxo-1-(phenylamino)butan-2-ylidene)hydrazinyl)benzenesulfonate) and [Ni(H2Lsu

Copper(II) arylhydrazone complexes as catalysts for C[sbnd]H activation in the Henry reaction in water

Three new water-soluble copper(II) complexes [Cu(HL)(H2O){(CH3)2NCHO}] (1), [Cu(H2L)2(im)4]·CH3OH (2) and [Cu(HL)(CH3OH)]2(μ2-py) (3) were synthe

Copper(II) coordination polymers of arylhydrazone of 1H-indene-1,3(2H)-dione linked by 4,4′-bipyridineor hexamethylenetetramine: Evaluation of catalytic activity in Henry reaction

The 1D and the 2D copper(II) coordination polymers [{Cu(κN,OO′-L)}2(μ-1κN:2κN′-bpy)2]n (1) and [{Cu(μ-1κN,OO′:2κO″-L)}2(μ-1κN:2κN′-hmt)]n (2), respectively, were synthesized from copper(II) nitrate and sodium 2-(2-(1,3-dioxo-1H-inden-2(3H)-ylidene) hydrazinyl)benzenesulfonate (NaHL), in the presence of 4,4′-bipyridine (4,4′-bpy) (for 1) or hexamethylenetetramine (hmt) (for 2). 1 and 2 are water soluble and are characterized by elemental analysis, IR spectroscopy, ESI-MS and single crystal X-ray diffraction. Depending on the neutral linkers, the dianionic ligand L2? displays tri- (in 1) or tetradentate (in 2) binding modes. The Cu2+ in 1 adopts a distorted N3O2 square-pyramid coordination environment, while in 2 it displays a distorted N2O3 trigonal bipyramid geometry. The catalytic activity of 1 and 2 was evaluated in the diastereoselective Henry reaction of nitroethane with a variety of aromatic and aliphatic aldehydes, in water and in organic solvents. β-Hydroxy nitroalkanes were obtained in high yields (up to 92%), and moderate-to-good syn/anti diastereoselectivities (up to 79:21), in water at room temperature.

Nanoporous lanthanide metal-organic frameworks as efficient heterogeneous catalysts for the Henry reaction

A series of self-assembled lanthanide coordination polymers formulated as [La(L1)2]n·1n(DMF)H·3n(DMF) (1), [Ce(L1)2]n·1n(DMF)H·2n(DMF) (2), [Sm(L1)2]n·1n(HCONH2)H·2n(HCONH2) (3), [La(L2)(HL2)(H2O)(DMF)2]n (4) and [Ce(L2)(HL2)(H2O)(DMF)2]n (5) [H2L1: 2-acetamidoterephthalic acid and H2L2: 2-benzamidoterephthalic acid] has been synthesized from the reactions of H2L1 or H2L2 with different lanthanide salts under hydrothermal conditions and characterized by elemental analysis, IR spectroscopy, X-ray single-crystal diffraction, powder X-ray diffraction, thermogravimetry and photoluminescence spectroscopy. X-ray diffraction analyses reveal that frameworks 1-3 have similar types of three-dimensional structures, composed of L12- ligands and trinuclear lanthanide nodes, in which two crystallographically independent lanthanide atoms are present. Frameworks 4 and 5 are isostructural, featuring a double chain-type one-dimensional coordination polymer which expands to 3D by means of H-bond interactions. These frameworks act as heterogeneous polymeric solid catalysts for the nitroaldol (Henry) reaction of different aldehydes with nitroalkanes, in water, and can be recycled without losing appreciable activity.

Metal-Organic Frameworks with Pyridyl-Based Isophthalic Acid and Their Catalytic Applications in Microwave Assisted Peroxidative Oxidation of Alcohols and Henry Reaction

Reactions of 5-{(pyridin-4-ylmethyl)amino} isophthalic acid (H2L1) with copper(II), zinc(II), and cadmium(II) were studied, and the obtained metal-organic frameworks (MOFs) [{Cu(L1)(DMF)}·DMF·H2O]n (1), [Zn(L1)(H2/su

1D Zn(II) coordination polymer of arylhydrazone of 5,5-dimethylcyclohexane-1,3-dione as a pre-catalyst for the Henry reaction

Reaction of a new hydrazone of β-diketone, 5-(2-(4,4-dimethyl-2,6-dioxocyclohexylidene)hydrazinyl)isophthalic acid (H3L), with zinc(II) nitrate hexahydrate in a mixture of DMF and water (1:1) under hydrothermal conditions affords the 1D coordin

The synthesis, structure, topology and catalytic application of a novel cubane-based copper(ii) metal-organic framework derived from a flexible amido tripodal acid

A novel chiral metal-organic framework, [Cu4(HL)2(H2O)4(MeO)4]n (1), has been successfully synthesized from a tripodal flexible ligand (2S,2′S,2"S)-2,2′,2"-(benzenetricarbonyltris(azanediyl