A general regioselective synthesis of 2,4-diarylpyrimidines from 2-thiouracil through two orthogonal cross-coupling reactions
A novel efficient synthesis of 2,4-diarylpyrimidines was developed based on phosphonium-mediated Suzuki coupling of 2-(methylsulfanyl)pyrimidin-4(3H)-one (at position 4) followed by the Liebeskind-Srogl cross-coupling (at position 2) under microwave irradiation. Georg Thieme Verlag Stuttgart · New York.
?erňová, Miroslava,Pohl, Radek,Klepetá?ová, Blanka,Hocek, Michal
supporting information; experimental part
p. 1305 - 1308
(2012/06/30)
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