139001-49-3

Basic information

• Product Name: PROFOXYDIM-LITHIUM
• Synonyms: TETRIS;PROFOXYDIM;PROFOXYDIM-LITHIUM;PROFOXYDIM LITHIUM SALT;BAS625H;AURA;CLEFOXYDIM LITHIUM SALT;CLEFOXYDIM
• CAS NO: 139001-49-3
• Molecular Formula: C₂₄H₃₂ClNO₄S
• Molecular Weight: 471.97
• Mol File: 139001-49-3.mol

Chemical Properties

• Melting Point: <25 °C
• Boiling Point: 592.2°Cat760mmHg
• Flash Point: 312°C
• Appearance: /
• Density: 1.217g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.596
• Storage Temp.: -20°C
• Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
• PKA: 4.25±0.25(Predicted)
• Stability: Hygroscopic, Unstable in Solution
• CAS DataBase Reference: PROFOXYDIM-LITHIUM(CAS DataBase Reference)
• NIST Chemistry Reference: PROFOXYDIM-LITHIUM(139001-49-3)
• EPA Substance Registry System: PROFOXYDIM-LITHIUM(139001-49-3)

Safety Data

• Hazard Codes: Xn
• Statements: 21/22
• Safety Statements: 36/37
• WGK Germany: 3
• Hazardous Substances Data: 139001-49-3(Hazardous Substances Data)

Usage

Uses

Used in Agricultural Industry:
Profoxydim-Lithium is used as a herbicide for controlling a wide range of grass and broadleaf weeds in various crops, including rice, wheat, and barley. It works by inhibiting the enzyme acetyl-CoA carboxylase, which is essential for fatty acid synthesis in plants, leading to the growth inhibition and eventual death of the weeds.
Additionally, Profoxydim-Lithium is used in combination with other herbicides to provide broader weed control and reduce the likelihood of weed resistance development. This combination approach also helps in managing the overall cost of weed control in agriculture.

Biochem/physiol Actions

G-protein-coupled receptor kinase 2 (GRK2) or ADRBK1 is a ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G protein-coupled receptors. GRK2 phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. RAF kinase inhibitor protein RKIP is a physiologic inhibitor of GRK2. After stimulation of G protein-coupled receptors, RKIP dissociates from its known target, RAF1 to associate with GRK2 and block its activity. G-protein-coupled receptor kinase 2 (GRK2) controls several intracellular mechanisms. It helps to maintain the structure and activities of the heart. Hence it participates in several cardiovascular diseases. GRK2 also modulates ion and fluid transport and eventually, blood pressure. It increases the synthesis of mitochondrial superoxide and reduces oxygen utilization and ATP synthesis. This protein serves as a major onco-modulator.

InChI:InChI=1/C24H32ClNO4S/c1-3-5-21(26-29-14-16(2)30-20-9-7-19(25)8-10-20)24-22(27)12-18(13-23(24)28)17-6-4-11-31-15-17/h7-10,16-18,27H,3-6,11-15H2,1-2H3/b26-21+

Downstream Products

• 281664-76-4 profoxydim-lithium 

Relevant articles and documents

NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND

An object of the present invention is to provide a compound having the controlling activity on a noxious arthropod, and a noxious arthropod controlling agent containing an amide compound of formula (I): wherein X represents a nitrogen atom or a CH group, p represents 0 or 1, A represents a tetrahydrofuranyl group or the like, R1, R2, R3, R4, R5, R6 and R7 represent a hydrogen atom or the like, n represents 1 or 2, Y represents an oxygen atom or the like, m represents any integer of 0 to 7, and Q represents a C1-8 chain hydrocarbon group optionally having a phenyl group or the like, has the excellent noxious arthropod controlling effect.

Herbicidal mixtures having a synergistic effect

PCT No. PCT/EP96/03996 Sec. 371 Date Feb. 17, 1998 Sec. 102(e) Date Feb. 17, 1998 PCT Filed Sep. 12, 1996 PCT Pub. No. WO97/10714 PCT Pub. Date Mar. 27, 1997A composition comprising at least one sulfonylurea of the formula I wherein R1 is substituted alkyl; halogen; a group ER6 (E=O, S or NR7); COOR8; NO2; S(O)oR9; SO2NR10R11; or CONR10R11; R2 is hydrogen, alkyl, alkenyl, alkynyl, halogen, alkoxy, haloalkoxy, haloalkyl, alkylsulfonyl, nitro, cyano or alkylthio; R3 is F, CF3, CF2Cl, CF2H, OCF3, OCF2Cl, or, if R1 is CO2CH3 and R2 is simultaneously fluorine, R3 is Cl, or, if R1 is CH2CF3 or CF2CF3, R3 is methyl, or, if R4 is OCF3 or OCF2Cl, R3 is OCF2H or OCF2Br; R4 is alkoxy, alkyl, alkylthio, alkylamino, dialkylamino, halogen, haloalkyl or haloalkoxy; and R5 is hydrogen, alkoxy or alkyl; or an enviromentally compatible salt of I, and an aryloxyalkanoic acid selected from the group consisting of 2,4-D, 2,4-DB, clomeprop, dichlorprop, dichlorprop-P, dichlorprop-P (2,4-DP-P), fenoprop (2,4,5-TP), fluoroxypyr, MCPA, MCPB, mecoprop, mecoprop-P, napropamide, napropanilide, triclopyr, and an enviromentally compatible salt thereof exhibits a synergistic herbicidal effect.