Synthesis, structure, and antimicrobial activity of heterocyclic phenylsulfonyl- and 4-aminophenylsulfonyl-carboximidamides
A series of novel phenylsulfonyl- and 4-amino-phenylsulfonyl- carboximidamides were synthesized by condensation of sulfonamides with heterocyclic methyl carbimi-dates obtained from heterocyclic carbonitriles and used 'at its inception.' The molecular structure of the obtained compounds is discussed. Compounds possessing heterocyclic systems with a nitrogen atom in the α position to the functional group showed a different single-crystal structure than expected. The synthesized derivatives were evaluated for antimicrobial activities: tuberculostatic, antibacterial, and antifungal.
Gobis, Katarzyna,Foks, Henryk,Wisniewska, Katarzyna,Dabrowska-Szponar, Maria,Augustynowicz-Kopec, Ewa,Napiorkowska, Agnieszka,Sikorski, Artur
experimental part
p. 1161 - 1169
(2012/10/08)
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