Synthesis of Bicyclic Pyridone and Dihydropyridone Analogues of β-Lactam Antibiotics
Condensation of the vinylogous urethanes 2, 26, 28 and 29 with acrylates, haloacrylates and propiolic acid has afforded easy access to bicyclic dihydropyridone and pyridone analogues of cephalosporins, carbapenams, penicillins and bisnorpenicillins.Synthe
Capps, Nigel K.,Davies, Gareth M.,Loakes, David,McCabe, Richard W.,Young, Douglas W.
p. 3077 - 3086
(2007/10/02)
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