- One-pot synthesis of thiazolo[3,4-a]quinoxalines and the related heterocyclic systems using 4-hydroxy-4-alkoxycarbonyl-3,5-diaryl-2- aryliminothia(selena)zolidines as versatile reagents
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An efficient and versatile one-step method for the synthesis of thiazolo[3,4-a]quinoxalines and related new heterocyclic systems have been developed on the basis of a new strategy for the construction of the pyrazine ring system. The key step of the process involves the cascade annulation of the iminothiazolopyrazine system to benzene in the reaction of 4-hydroxy-3,5-diaryl- 2-phenyliminothiazolidines with 1,2-diaminobenzenes. The use of selenium analogues instead of thiazolidine derivatives in this reaction, leads to selenazolo[3,4-a]quinoxalines and the use of aza analogues instead of 1,2-diaminobenzenes gives aza analogues of thiazolo[3,4-a]quinoxalines.
- Mamedov, Vakhid A.,Zhukova, Nataliya A.,Balandina, Alsu A.,Kharlamov, Sergey V.,Beschastnova, Tat'Yana N.,Rizvanov, Il'Dar Kh.,Latypov, Shamil K.
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