Process research for multikilogram production of etamicastat: A novel dopamine β-hydroxylase inhibitor
In order to develop a manufacturing route to etamicastat, three synthetic approaches to the pivotal chiral 3-aminochroman intermediate have been studied as well as four methods for the construction of the 2-aminoethyl imidazolethione fragment. The evoluti
Beliaev, Alexandre,Wahnon, Jorge,Russo, Domenico
scheme or table
p. 704 - 709
(2012/07/03)
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