13952-76-6Relevant articles and documents
Synthesis of betulin derivatives and their protective effects against the cytotoxicity of cadmium
Hiroya, Kou,Takahashi, Taisuke,Miura, Nobuhiko,Naganuma, Akira,Sakamoto, Takao
, p. 3229 - 3236 (2007/10/03)
The protecting effect of betulin against cadmium toxicity was investigated using 11 inds of analogues. It was elucidated by analyzing the analogue activities that both hydroxyl groups on C-3 and C-28 and the isopropenyl group on C-19 played important roles for expressing efficient activities. In addition, the cytotoxicity of betulin was also reduced by being functionalized using the above functional group. Copyright