13980-14-8

Basic information

• Product Name: 2-HYDROXYDOCOSANOIC ACID
• Synonyms: DL-ALPHA-HYDROXYBEHENIC ACID;2-HYDROXY C22:0 ACID;2-HYDROXYDOCOSANOIC ACID;dl-A-hydroxybehenic acid;dl-α-hydroxybehenic acid;2-hydroxybehenic acid
• CAS NO: 13980-14-8
• Molecular Formula: C₂₂H₄₄O₃
• Molecular Weight: 356.58
• Mol File: 13980-14-8.mol

Chemical Properties

• Boiling Point: 484.2 °C at 760 mmHg
• Flash Point: 260.8 °C
• Appearance: /
• Density: 0.928 g/cm³
• Vapor Pressure: 2.07E-11mmHg at 25°C
• Refractive Index: 1.469
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-HYDROXYDOCOSANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HYDROXYDOCOSANOIC ACID(13980-14-8)
• EPA Substance Registry System: 2-HYDROXYDOCOSANOIC ACID(13980-14-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 13980-14-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-HYDROXYDOCOSANOIC ACID is used as an active pharmaceutical ingredient for its potential therapeutic effects. The hydroxy group at the 2nd position allows for interactions with biopolymers and macromolecules, making it a promising candidate for the development of new drugs.
Used in Cosmetic Industry:
In the cosmetic industry, 2-HYDROXYDOCOSANOIC ACID is used as an ingredient in skincare and hair care products due to its moisturizing and emollient properties. The long-chain structure of the fatty acid helps to form a protective barrier on the skin, retaining moisture and providing a smooth texture.
Used in Chemical Industry:
2-HYDROXYDOCOSANOIC ACID is used as a building block for the synthesis of various chemical compounds, such as surfactants, lubricants, and additives. Its unique structure allows for the creation of tailored products with specific properties for different applications.
Used in Research and Development:
In the field of research and development, 2-HYDROXYDOCOSANOIC ACID serves as a valuable compound for studying the effects of hydroxy group substitution on the properties and behavior of long-chain fatty acids. This knowledge can be applied to the design of new materials and the optimization of existing ones.
Used in Biotechnology:
2-HYDROXYDOCOSANOIC ACID is used as a substrate or intermediate in the biotechnological production of bioactive compounds, such as biofuels, bioplastics, and other bio-based materials. Its unique structure makes it a versatile building block for the development of sustainable and eco-friendly products.

InChI:InChI=1/C22H44O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21(23)22(24)25/h21,23H,2-20H2,1H3,(H,24,25)

Upstream product

• 5908-87-2 ethyl docosanoate 
• 260055-71-8 2-acetoxy-docosanoic acid ethyl ester 
• 64-17-5 ethanol 
• 20828-43-7 α-bromobehenic acid 

Downstream Products

• 260055-72-9 2-hydroxy-docosanoic acid benzyl ester 
• 260055-70-7 2-Trifluoromethanesulfonyloxy-docosanoic acid benzyl ester 

Relevant articles and documents

Role of the hydrophobic moiety of tumor promoters. Synthesis and activity of 2-alkylated benzolactams

The size and position of a hydrophobic moiety on a benzolactam skeleton, which reproduces the active conformation and biological activity of teleocidins, play an important role in the appearance of the activity. Compounds with alkyl groups of various sizes and shapes at the 2-position of benzolactam were synthesized. Structure-activity results indicate that a hydrophobic substituent at the C-2 position plays a critical role in the appearance of biological activities, as in the case of substitution at C-9.

Synthesis of Long Chain Substituted cis- and trans-2-Trichloromethyldioxolanones.

Reaction of chloral hydrate with α-hydroxy derivatives of palmitic (Ia), stearic (Ib) and behenic (Ic) acids gave the corresponding cis-2-trichloromethyldioxolanones (IIa,b,c) and trans-2-trichloromethyldioxolanones (IIIa,b,c), yields being ca. 50percent for each reaction product.The structures of the individual reaction products were established clearly by elemental analysis as well as by spectral studies.