1398609-80-7

Basic information

• Product Name: tert-butyl 5'-bromo-3'H-spiro[azetidine-3,1'-[2]benzofuran]-1-carboxylate
• Synonyms: tert-butyl 5'-bromo-3'H-spiro[azetidine-3,1'-[2]benzofuran]-1-carboxylate;tert-Butyl 5'-bromo-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-carboxylate
• CAS NO: 1398609-80-7
• Molecular Weight: 0
• Mol File: 1398609-80-7.mol

Chemical Properties

• CAS DataBase Reference: tert-butyl 5'-bromo-3'H-spiro[azetidine-3,1'-[2]benzofuran]-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 5'-bromo-3'H-spiro[azetidine-3,1'-[2]benzofuran]-1-carboxylate(1398609-80-7)
• EPA Substance Registry System: tert-butyl 5'-bromo-3'H-spiro[azetidine-3,1'-[2]benzofuran]-1-carboxylate(1398609-80-7)

Safety Data

• Hazardous Substances Data: 1398609-80-7(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Tert-butyl 5'-bromo-3'H-spiro[azetidine-3,1'-[2]benzofuran]-1-carboxylate is used as a key intermediate in organic synthesis for the creation of novel bioactive molecules. Its unique structure and functional groups facilitate the development of a wide range of chemical compounds with potential applications in various industries.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, tert-butyl 5'-bromo-3'H-spiro[azetidine-3,1'-[2]benzofuran]-1-carboxylate is utilized as a building block for the design and synthesis of new pharmaceuticals. Its spirocyclic structure and functional groups contribute to the discovery of innovative drug candidates with potential therapeutic benefits.
Used in Pharmaceutical Development:
Tert-butyl 5'-bromo-3'H-spiro[azetidine-3,1'-[2]benzofuran]-1-carboxylate is employed as a crucial component in the development of new drugs. Its unique structure and properties make it a promising candidate for the creation of pharmaceuticals with improved efficacy, selectivity, and safety profiles.
Used in Agrochemical Development:
tert-butyl 5'-bromo-3'H-spiro[azetidine-3,1'-[2]benzofuran]-1-carboxylate is also used in the development of agrochemicals, where its unique structure and functional groups can contribute to the creation of novel pesticides, herbicides, and other agricultural chemicals. tert-butyl 5'-bromo-3'H-spiro[azetidine-3,1'-[2]benzofuran]-1-carboxylate's potential applications in this industry can lead to the development of more effective and environmentally friendly products.
Used in Material Science:
Tert-butyl 5'-bromo-3'H-spiro[azetidine-3,1'-[2]benzofuran]-1-carboxylate finds applications in material science, where its unique structure and properties can be leveraged to develop new materials with specific properties. These materials can be used in various applications, such as coatings, adhesives, and other industrial products.

Upstream product

• 398489-26-4 tert-butyl 3-oxoazetidine-1-carboxylate 
• 1261817-10-0 4-bromo-2-(chloromethyl)-1-iodobenzene 
• 1261553-12-1 4-bromo-1-(chloromethyl)-2-iodobenzene 

Downstream Products

• 1398610-04-2 tert-butyl 6-[(E/Z)-3-(3,5-dichloro-4-fluoro-phenyl)-4,4,4-trifluoro-but-2-enoyl]spiro[1H-isobenzofuran-3,3'-azetidine]-1'-carboxylate 
• 1398609-81-8 tert-butyl 5'-acetyl-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-carboxylate 
• 1575810-99-9 tert-butyl 5'-[3-(3,5-dichloro-4-fluorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]-3'H-spiro[azetidine-3,1'-[2]benzofuran]-1-carboxylate 
• 1575811-05-0 tert-butyl 5'-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]-3'H-spiro[azetidine-3,1'-[2]benzofuran]-1-carboxylate 
• 1575811-10-7 tert-butyl 5'-[3-(3,4,5-trichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]-3'H-spiro[azetidine-3,1'-[2]benzofuran]-1-carboxylate 
• 1575811-03-8 5'-[3-(3,5-dichloro-4-fluorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]-3'H-spiro[azetidine-3,1'-[2]benzofuran] 
• 1575794-94-3 5'-[3-(3,5-dichloro-4-fluorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]-1-isobutyryl-3'H-spiro[azetidine-3,1'-[2]benzofuran] 
• 1575811-07-2 5'-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]-3'H-spiro[azetidine-3,1'-[2]benzofuran] 
• 1575795-00-4 5'-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidine-1-yl]-1-[(methylsulfonyl)acetyl]-3'H-spiro[azetidine-3,1'-[2]benzofuran] 
• 1575795-02-6 5'-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]-1-isobutyryl-3'H-spiro[azetidine-3,1'-[2]benzofuran] 
• 1575810-06-8 tert-butyl 5'-(4,4,4-trifluoro-3-(3,4,5-trichlorophenyl)but-2-enoyl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-carboxylate 
• 1575811-13-0 5'-[3-(3,4,5-trichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]-3'H-spiro[azetidine-3,1'-[2]benzofuran] 
• 1575795-11-7 1-isobutyryl-5'-[3-(3,4,5-trichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]-3'H-spiro[azetidine-3,1'-[2]benzofuran] 
• 1575810-08-0 tert-butyl 5'-(4,4,4-trifluoro-3-(nitromethyl)-3-(3,4,5-trichlorophenyl)butanoyl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-carboxylate 

Relevant articles and documents

PESTICIDAL AND PARASITICIDAL PYRAZOLE-ISOXAZOLINE COMPOUNDS

The present invention relates to pesticidal and parasiticidal isoxazoline of formula (I) and salts thereof: wherein variables R1, P, Y and Q are described herein are as defined in the description. The invention also relates to parasiticidal and pesticidal compositions comprising the isoxazoline compounds of formula (I), processes for their preparation and their uses to prevent or treat parasitic infections or infestations in animals and as pesticides.

ANTIPARASITIC COMPOUNDS

The present invention relates to isothiazoline compounds of formula (I). The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to veterinary compositions comprising said compounds.

ANTIPARASITIC COMPOUNDS

The present invention relates to isothiazoline compounds of formula (I). The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to veterinary compositions comprising said compounds.

CRYSTALLINE FORMS OF 1-(5'-(5-(3,5-DICHLORO-4-FLUOROPHENYL)-5-(TRIFLUOROMETHYL)-4,5-DIHYDROISOXAZOL-3-YL)-3'H-SPIRO[AZETIDINE-3,1'-ISOBENZOFURAN]-1-YL)-2-(METHYLSULFONYL)ETHANONE

The present invention relates to novel crystalline modifications of 1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethanone. The present invention also describes compositions and methods of treating a parasitic infection or infestation in an animal in need thereof. The present invention also relates to processes for making the crystalline forms.

SPIROCYCLIC DERIVATIVES AS ANTIPARASITIC AGENTS

The invention recites spirocyclic derivatives of Formula (V.1) or (V.2), stereoisomers thereof, veterinary acceptable salts thereof, compositions thereof, processes for making, and their use as a parasiticide for an animal. The variables A, B, V, Z, Y, W1, W2, W3, R1a, R1b, R1c, R2, R3, R4, n, and "---" are as described herein.

SPIROCYCLIC ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS

The invention recites spirocyclic isoxazoline derivatives of Formula (V.1), Formula (V.2), Formula (V.1.1), and Formula (1) stereoisomers thereof, veterinarily acceptable salts thereof, compositions thereof, processes for making, and their use as a parasi