140160-96-9Relevant articles and documents
Synthesis, characterization, and fluorescence behavior of four novel macrocyclic emissive ligands containing a flexible 8-hydroxyquinoline unit
Nú?ez, Cristina,Bastida, Rufina,Macías, Alejandro,Bértolo, Emilia,Fernandes, Luz,Capelo, José Luis,Lodeiro, Carlos
, p. 6179 - 6188 (2009)
Four emissive macrocyclic ligands mono-substituted with an 8-hydroxyquinoline pendant arm are presented. The new compounds have been used for metal-ion detection, which results from the competition between PET (photo-induced electron transfer) and PPT (ph
Stereoselective synthesis of oxazolidine, hexahydropyrrolo [2,1-b] oxazole, and tetrahydro-2H-oxazolo [3,2-c] thiazole grafted macrocycles through intramolecular 1,3-dipolar cycloaddition reaction
Purushothaman,Raghunathan
, p. 6848 - 6850 (2009)
A facile one-pot synthesis of oxazolidine, hexahydropyrrolooxazole and tetrahydro-2H-oxazolothiazole grafted macrocycles through intramolecular 1,3-dipolar cycloaddition reaction (1,3-DC reaction) is reported. X-ray diffraction studies and 2D NOESY experi
Study on the synthesis of novel fluorescent macrocyclic sensors and their sensitive properties for Cu2+ and Fe3+ in aqueous solution
Dai, Yanpeng,Xu, Kuoxi,Wang, Chaoyu,Liu, Xiaoyan,Wang, Peng
, p. 315 - 322 (2017)
In this work, we synthesised and characterised three novel fluorescence macrocyclic sensors containing optically active dansyl groups. The studies for the interaction of the synthesised compounds with various mental ions (Li+, Na+, K+, Ag+, Mg2+, Ca2+, Ba2+, Pb2+, Zn2+, Co2+, Cd2+, Hg2+, Ni2+, Cu2+, Mn2+, Cr3+, Al3+, Fe3+) were performed by fluorescence titration, Job’s plot, ESI-MS and DFT calculations. The results showed that the sensors 1a–1c displayed selective recognition for Cu2+ and Fe3+ ions and formed stoichiometry 1:1 complex through PET mechanism in DMSO/H2O solution (1:1, v/v, pH 7.4 of HEPES). The binding constant (K) and detection limit were calculated.
Coordination behaviors of a 23-membered NO4S2-macrocycle: Mononuclear silver(I) complex and conformational isomers of tetranuclear bis(macrocycle) mercury(II) complexes exhibiting exo- and endo/exocyclic coordination modes
Shin, Mingyeong,Ju, Huiyeong,Habata, Yoichi,Lee, Shim Sung
, p. 749 - 755 (2018)
A ditopic 23-membered NO4S2-macrocycle (L) incorporating both semi-rigid and flexible binding sites was synthesized and its silver(I) and mercury(II) complexes exhibiting different stoichiometries and coordination modes were prepared. First, silver(I) perchlorate reacts with L to afford an endocyclic mononuclear complex [Ag(L)]ClO4 (1) in which the silver(I) ion locates at the semi-rigid binding site in the cavity. The solution study for the silver(I) complexation via the 1H NMR titration agrees with the corresponding solid state data that show the endo-mode. Interestingly, the reaction of L with HgI2 led to the isolation of two conformational isomers with a tetranuclear bis(macrocycle) composition, [(exoHgLI2)2(μ-Hg2I4)] (2a) and [(endoHgLI2)2(μ-Hg2I4)] (2b), which are dominated by the coordination modes of L toward the mercury(II) center. In both conformers, two exocyclic mercury(II) complex units (exoHgLI2)2 in 2a or two endocyclic complex units [(endoHgLI2)2 in 2b are linked by tetraiododimercury(II) core (μ-Hg2I4) to give a 4:2 (metal-to-ligand) stoichiometry. Based on the packing structures and high temperature experiment, the intermolecular interactions might be responsible for the formation of 2a and 2b which are kinetically and thermodynamic controlled, respectively.
Short-chain Basket Handle Porphyrins: Synthesis and Characterisation
Reddy, Damodar,Chandrashekar, Tavarekere K.
, p. 619 - 626 (1992)
Basket handle porphyrins containing short p- or m-phenylenedimethylenedioxy chains covalently linked at the ortho position of phenyl groups of 5,10,15,20-tetraphenylporphyrin have been synthesised.Isomer I of the para derivative (H2LIa) and iso
Radiosynthesis, in vitro and preliminary biological evaluation of [18F]2-amino-4-((2-((3-fluorobenzyl)oxy)benzyl)(2-((3-(fluoromethyl)benzyl)oxy)benzyl)amino)butanoic acid, a novel alanine serine cysteine transporter 2 inhibitor-based positron
Baguet, Tristan,Bouton, Jakob,De Vos, Filip,Descamps, Benedicte,Janssens, Jonas,Pauwelyn, Glenn,Van Calenbergh, Serge,Vanhove, Christian,Verhoeven, Jeroen
, (2020)
The metabolic alterations in tumors make it possible to visualize the latter by means of positron emission tomography, enabling diagnosis and providing metabolic information. The alanine serine cysteine transporter-2 (ASCT-2) is the main transporter of gl
An entry into new classes of optically active aza-oxo polyether macrocycles via the ring closing metathesis-based macrocyclization
Naveen,Babu, Srinivasarao Arulananda
, p. 5690 - 5694 (2016)
We report the application of ring closing metathesis-based macrocyclization route for synthesizing 22–36 membered optically active aza-oxo crowns/polyether macrocycles. While the RCM-based synthesis of polyether macrocycles was well explored in the literature, the synthesis of optically active polyether macrocycles was not explored via the RCM reaction. Accordingly, the present method reveals an efficient assembling of a library of new classes of optically active aza-oxo polyether macrocycles from optically active RCM precursors, which were assembled from easily available linkers, chiral α-methylbenzylamine and amino alcohol building blocks under simple reaction conditions.
Exploitation of Intramolecular Glaser-Eglinton-Hay Macrocyclization for the Synthesis of New Classes of Optically Active Aza-Oxo-Thia Polyether Macrocycles from Amino Alcohol Building Blocks
Babu, Srinivasarao Arulananda
, p. 253 - 259 (2017)
We report an intramolecular Glaser-Eglinton-Hay coupling as an unprecedented route for assembling optically active aza-oxo polyether macrocycles containing a 1,3-diyne unit from enantiopure amino alcohol building blocks and suitable linkers. Furthermore, the conversion of the 1,3-diyne unit of the aza-oxo polyether macrocycles into a thiophene ring led to the assembly of new classes of optically active aza-oxa-thia (heterotopic) polyether macrocycle analogues of classical 18-C-6 and 18-C-5 systems.
Synthesis and characterization of two new macrobicyclic salts containing hexahydropyrimidine moieties: experimental and density functional theory studies
Keypour, Hassan,Babeli, Simin,Zeynali, Hamid,Bayat, Mehdi,Rezaeivala, Majid
, p. 2549 - 2555 (2017)
Two macrocyclic Schiff base ligands (L1, L2) and their related reduced forms (L3 and L4) have been prepared. In the presence of nickel(II) perchlorate in methanol, the reinforced macrobicyclic salts containing h
Microwave assisted multi-component synthesis of novel bis(1,4-dihydropyridines) based arenes or heteroarenes
Sanad, Sherif M. H.,Kassab, Refaie M.,Abdelhamid, Ismail A.,Elwahy, Ahmed H. M.
, p. 910 - 924 (2016/07/06)
A synthesis of novel bis-1,4-DHPs was reported. Two possible synthetic approaches for these compounds were investigated. In the first approach the monopodal 1,4-DHPs were used as building blocks for the construction of the target molecules via a simple al
