An efficient synthesis of 4-chloro-2-pyrrolino[2,3- d ]pyrimidin-6-one and its 7-substituted analogues
An efficient synthesis of 4-chloro-2-pyrrolino[2,3-d]pyrimidin-6-one was achieved in four steps starting from dimethyl malonate in 23% overall yield. This synthesis was demonstrated on 100 g scale to obtain 4-chloro-2-pyrrolino[2, 3-d]pyrimidin-6-one in 9
Vaid, Radhe K.,Spitler, Jeremy T.,Boini, Sathish,May, Scott A.,Hoying, Richard C.
p. 2396 - 2400
(2012/10/08)
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