1402742-12-4

Basic information

• Product Name: C₁₉H₂₂FNO₂S
• Synonyms: C₁₉H₂₂FNO₂S
• CAS NO: 1402742-12-4
• Molecular Weight: 347.454
• Mol File: 1402742-12-4.mol

Chemical Properties

• CAS DataBase Reference: C₁₉H₂₂FNO₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₂₂FNO₂S(1402742-12-4)
• EPA Substance Registry System: C₁₉H₂₂FNO₂S(1402742-12-4)

Safety Data

• Hazardous Substances Data: 1402742-12-4(Hazardous Substances Data)

Upstream product

• 30379-55-6 benzyloxyacetic acid 
• 1402742-11-3 C₁₅H₁₃FO₂ 
• 146374-27-8 S-tert-butylsulfinimide 
• 1072-85-1 o-fluorobromobenzene 
• 104863-68-5 2-(benzyloxy)-N-methoxy-N-methylacetamide 

Downstream Products

• 1402742-33-9 C₃₀H₄₀FN₃O₈S 
• 1402742-34-0 C₃₀H₃₈FN₃O₈S 
• 1402742-38-4 C₁₈H₂₃FN₄O₇S 
• 1402742-42-0 C₃₆H₅₄FN₃O₉SSi 
• 1402742-45-3 C₂₄H₃₆FN₃O₆SSi 
• 1402742-15-7 C₁₇H₂₁FN₂O₃S 
• 1402742-16-8 C₁₈H₂₀FN₃O₃S 
• 1402742-17-9 C₂₈H₃₆FN₃O₇S 
• 1402742-18-0 C₃₀H₄₀FN₃O₈S 

Relevant articles and documents

C5-C6-CARBOCYCLIC FUSED IMINOTHIADIAZINE DIOXIDES AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE

In its many embodiments, the present invention provides certain C5-C6-carbocyclic fused iminothiazine dioxide compounds, including compounds Formula (I): and tautomers thereof, and pharmaceutically acceptable salts of said compounds and said tautomers, wherein R1, ring A, RA, m, -L1-, ring B, RB, n, q, ring C, RC, and p are as defined herein. The novel compounds of the invention are useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including for the possible treatment of Alzheimer's disease, are also disclosed.

C5-C6-OXACYLIC FUSED IMINOTHIAZINE DIOXIDE COMPOUNDS BEARING AN ETHER LINKER AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE

In its many embodiments, the present invention provides certain C5-C6-oxacyclic fused iminothiazine dioxide compounds bearing an ether linker, including compounds Formula (I) or a tautomer thereof, and pharmaceutically acceptable salts of said compounds a

C5-C6-OXACYLIC FUSED IMINOTHIADIAZINE DIOXIDE COMPOUNDS BEARING AN ETHER LINKER AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE

In its many embodiments, the present invention provides certain C5-C6-oxacyclic fused iminothiadiazine dioxide compounds bearing an ether linker, including compounds Formula (I): or a tautomer thereof, and pharmaceutically acceptable salts of said compoun

C5, C6 OXACYCLIC-FUSED IMINOTHIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS

In its many embodiments, the present invention provides certain C2-ring-substituted iminothiazine compounds, including compounds Formula (I): (structurally represented) or a tautomers thereof, and pharmaceutically acceptable salts of said compounds and, w

C5-C6 OXACYCLIC-FUSED THIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE

In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula : (I) and tautomers and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds, said tautomeros and said stereoisomers, wherein each of ring A, ring B, ring C, R2, R3, R4, m, n, p, and -L1- is as defined herein. The novel compounds of the invention may be useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including Alzheimer's disease, are also disclosed.