14034-99-2

Basic information

• Product Name: 4-bromo-2-tert-butylbenzoic acid
• Synonyms: 4-bromo-2-tert-butylbenzoic acid
• CAS NO: 14034-99-2
• Molecular Formula: C₁₁H₁₃BrO₂
• Molecular Weight: 257.12372
• Mol File: 14034-99-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-bromo-2-tert-butylbenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2-tert-butylbenzoic acid(14034-99-2)
• EPA Substance Registry System: 4-bromo-2-tert-butylbenzoic acid(14034-99-2)

Safety Data

• Hazardous Substances Data: 14034-99-2(Hazardous Substances Data)

Upstream product

• 14034-97-0 4-Nitro-2-tert.-butyl-benzoesaeure 
• 14034-96-9 2-tert-butyl-4-nitrobenzonitrile 
• 59255-98-0 2-(tert-butyl)-4-nitroaniline 
• 14034-98-1 4-Amino-2-tert.-butyl-benzoesaeure 

Relevant articles and documents

AMINO ALCOHOL DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USE OF THESE

The present invention provides compounds represented by general formula (I): a prodrug thereof, or pharmaceutical acceptable salts thereof, wherein R1 is hydrogen or lower alkyl; each of R2 and R3 is independently hydrogen or lower alkyl; each of R4, R5 and R6 is independently hydrogen, halogen, lower alkyl or lower alkoxy; R7 is hydrogen or lower alkyl; R8 is hydrogen, halogen, lower alkyl, lower alkoxy, etc; R9 is -COR10, -A1-COR10, -O-A2-COR10, etc; Ar is optionally substituted phenyl or heteroaryl; and A is a bond, -OCH2-, etc, which exhibit potent and selective β3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.

AMINO ALCOHOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND USE THEREOF

The present invention provides compounds represented by general formula (I): or pharmaceutical acceptable salts thereof, wherein R1 and R2 are each hydrogen or lower alkyl; R3 R4, R5 and R6 are each hydrogen, halogen, lower alkyl or lower alkoxy; R7 and R8 are each hydrogen, halogen, lower alkyl, halo-lower alkyl, lower alkoxy, cycloalkyl, aryl, heteroaryl, cyano, a hydroxyl group, lower acyl, carboxy or the like; R9 is -C(O)-R10, -A1-C(O)-R10, -O-A2-C(O)-R10 or a tetrazol-5-yl group, which exhibit potent and selective β3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.