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Chloroprednisone 21-acetate is a synthetic corticosteroid derived from prednisone, characterized by the addition of a chloro group and a 21-acetate group. This modification enhances its anti-inflammatory properties and improves bioavailability and duration of action, making it a potent medication for managing inflammation and immune system suppression.

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  • 14066-79-6 Structure
  • Basic information

    1. Product Name: chloroprednisone 21-acetate
    2. Synonyms: chloroprednisone 21-acetate;21-Acetyloxy-6α-chloro-17-hydroxypregna-1,4-diene-3,11,20-trione
    3. CAS NO:14066-79-6
    4. Molecular Formula: C23H27ClO6
    5. Molecular Weight: 434.90988
    6. EINECS: 237-919-3
    7. Product Categories: N/A
    8. Mol File: 14066-79-6.mol
  • Chemical Properties

    1. Melting Point: 217-219°
    2. Boiling Point: 614.9°Cat760mmHg
    3. Flash Point: 325.7°C
    4. Appearance: /
    5. Density: 1.34g/cm3
    6. Vapor Pressure: 1.08E-17mmHg at 25°C
    7. Refractive Index: 1.585
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: chloroprednisone 21-acetate(CAS DataBase Reference)
    11. NIST Chemistry Reference: chloroprednisone 21-acetate(14066-79-6)
    12. EPA Substance Registry System: chloroprednisone 21-acetate(14066-79-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 14066-79-6(Hazardous Substances Data)

14066-79-6 Usage

Uses

Used in Pharmaceutical Industry:
Chloroprednisone 21-acetate is used as an anti-inflammatory and immunosuppressant medication for treating various conditions such as allergies, asthma, and autoimmune diseases. The enhanced anti-inflammatory effect and improved bioavailability due to the chloro and 21-acetate groups allow for a more effective and prolonged therapeutic response in reducing inflammation and suppressing the immune system.
Used in Allergy Treatment:
Chloroprednisone 21-acetate is used as an anti-allergic medication to alleviate symptoms caused by allergic reactions. Its potent anti-inflammatory and immunosuppressive properties help in managing allergic conditions effectively.
Used in Asthma Management:
Chloroprednisone 21-acetate is used as a medication to control asthma symptoms by reducing inflammation in the airways, thereby improving lung function and reducing the frequency of asthma attacks.
Used in Autoimmune Disease Therapy:
Chloroprednisone 21-acetate is used as an immunosuppressant in the treatment of autoimmune diseases, where the immune system mistakenly attacks the body's own tissues. Its ability to suppress the immune system helps in managing the symptoms and progression of autoimmune diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 14066-79-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,0,6 and 6 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 14066-79:
(7*1)+(6*4)+(5*0)+(4*6)+(3*6)+(2*7)+(1*9)=96
96 % 10 = 6
So 14066-79-6 is a valid CAS Registry Number.
InChI:InChI=1/C23H27ClO6/c1-12(25)30-11-19(28)23(29)7-5-15-14-9-17(24)16-8-13(26)4-6-21(16,2)20(14)18(27)10-22(15,23)3/h4,6,8,14-15,17,20,29H,5,7,9-11H2,1-3H3/t14-,15-,17-,20+,21-,22-,23-/m0/s1

14066-79-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name chloroprednisone 21-acetate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:14066-79-6 SDS

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