Design, synthesis and use of novel 3,3-disubstituted 2,2-bipyridine-based chiral ligands: Asymmetric catalysis in direct aldol reactions
A wide range of chiral ligands based on the 2,2-bipyridine scaffold were designed and synthesized. In complexation with metal Lewis acids, the reactivity and stereoselectivity of the prepared chiral ligands were examined in asymmetric catalytic direct ald