Asymmetrical ene reaction of 2-methylpropene with 2,3-dichloropropanal and chloral in the presence of chiral methyloxyaluminum dichloride
The catalytic ene reaction of 2-methylpropene with 2,3-dichloropropanal and chloral was carried out in the presence of l-methyloxyaluminum dichloride, leading to optically active homoallylic chlorohydrins with good enantiomeric purity.