14123-78-5 Usage
Uses
Used in Pharmaceutical Research and Development:
(R)-3-METHYL 3,4-DIHYDROISOQUINOLINE HYDROCHLORIDE is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure and potential biological activities make it a valuable candidate for the development of new drugs.
Used in Medicinal Chemistry:
(R)-3-METHYL 3,4-DIHYDROISOQUINOLINE HYDROCHLORIDE is used as a building block in the design and synthesis of novel bioactive molecules. Its structural properties allow for the creation of new compounds with potential therapeutic applications.
Used in Neuropharmacology:
(R)-3-METHYL 3,4-DIHYDROISOQUINOLINE HYDROCHLORIDE is used as a research tool in neuropharmacology to study the interactions of isoquinoline-based compounds with various neurotransmitter systems. Its potential biological activities may contribute to the development of new treatments for neurological disorders.
Used in Analytical Chemistry:
(R)-3-METHYL 3,4-DIHYDROISOQUINOLINE HYDROCHLORIDE can be used as a reference compound in analytical chemistry for the development and validation of analytical methods, such as chromatography and mass spectrometry, for the detection and quantification of related compounds in biological samples.
Used in Organic Synthesis:
(R)-3-METHYL 3,4-DIHYDROISOQUINOLINE HYDROCHLORIDE serves as a versatile starting material in organic synthesis for the preparation of various isoquinoline-based derivatives. Its reactivity and functional group compatibility make it suitable for a wide range of synthetic transformations.
Check Digit Verification of cas no
The CAS Registry Mumber 14123-78-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,1,2 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 14123-78:
(7*1)+(6*4)+(5*1)+(4*2)+(3*3)+(2*7)+(1*8)=75
75 % 10 = 5
So 14123-78-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H11N/c1-8-6-9-4-2-3-5-10(9)7-11-8/h2-5,7-8H,6H2,1H3/t8-/m1/s1
14123-78-5Relevant articles and documents
Synthesis and Antihypertensive Activity of a Series of Spiroquinolizine-2,5'-oxazolidin-2'-one>s
Caroon, Joan M.,Clark, Robin D.,Kluge, Arthur F.,Lee, Chi-Ho,Strosberg, Arthur M.
, p. 1426 - 1433 (2007/10/02)
The 2R*,11bS* and 2S*,11bS* diastereoisomers of the spiroquinolizine-2,5'-oxazolidin-2'-one> system were prepared by stereoselective methods.Evaluation of these compounds for antihypertensive activity by oral administration to the spontaneously hypertensive rat showed the 2S*,11bS* series was the more potent.Within that series it was found that small alkyl substituents at positions 3 and 4' enhanced antihypertensive activity and that methoxyl substitution at positions 9 and 10 was optical. (2S,3S,11bS)-Spiroquinolizine-2,5'-oxazolidin-2'-one> was one of the most efficacious compounds of this series, while its antipode, (+)-9e, was inactive.Selected compounds in this series were shown to be α-adrenoceptor antagonists.
