14131-56-7Relevant articles and documents
Efficient enzymatic synthesis of guanosine 5′-diphosphate-sugars and derivatives
Li, Lei,Liu, Yonghui,Wan, Yue,Li, Yanhong,Chen, Xi,Zhao, Wei,Wang, Peng George
supporting information, p. 5528 - 5530 (2013/11/19)
An N-acetylhexosamine 1-kinase from Bifidobacterium infantis (NahK-15697), a guanosine 5′-diphosphate (GDP)-mannose pyrophosphorylase from Pyrococcus furiosus (PFManC), and an Escherichia coli inorganic pyrophosphatase (EcPpA) were used efficiently for a one-pot three-enzyme synthesis of GDP-mannose, GDP-glucose, their derivatives, and GDP-talose. This study represents the first facile and efficient enzymatic synthesis of GDP-sugars and derivatives starting from monosaccharides and derivatives.